The Zebrafish Chip - Organism-on-a-Chip - Fluidic 1371 is a microfluidic device designed to capture individual zebrafish eggs at fixed points for developmental observation. The channel allows for volume-controlled perfusion, and the chip supports straightforward volume selection due to its Mini Luer interface. It features a single meandering channel that accommodates sequential egg positioning and stable observation under flow.
General
The zebrafish chip Fluidic 1371, featuring Mini Luer interfaces, is capable of capturing individual zebrafish eggs at predefined monitoring positions. The catcher structures are arranged along a long, meandering channel. Once caught, the eggs will block the outlet of each catcher structure, and the resulting suction effect will keep them in place. Under constant perfusion, the development of zebrafish can then be observed. The design of this chip is based on the publication by J. Akagi et al. PLoS One (2012) [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036630].
Features & Benefits
- Individual Egg Capture: Each chip is designed to hold and monitor single zebrafish eggs at fixed locations. This allows for direct observation without manual repositioning.
- Stable Egg Positioning: The flow-driven suction mechanism keeps eggs in place once captured. This stability enhances reliability of developmental monitoring.
- Easy Perfusion and Sampling: The Mini Luer interface allows simple connection for liquid exchange or sample introduction during experiments.
This chip enables controlled observation of zebrafish egg development in a streamlined and efficient setup. With transparent material and a single channel layout, it provides direct visibility for real-time monitoring. The use of Mini Luer interfaces makes integration with laboratory equipment easy.
Researchers can observe eggs at precise positions along the channel. The robust catcher design ensures minimal movement during the experiment. It is based on peer-reviewed research and offers reproducible results for experimental work involving zebrafish embryos.
Applications
This product is ideal for controlled zebrafish embryo research and related applications where individual egg monitoring, perfusion, and developmental analysis are required.
- Developmental biology studies
- Pharmaceutical compound screening
- Toxicology assessment
Content
1x Zebrafish Chip - Organism-on-a-Chip - Fluidic 1371
Specifications
| SKU | CS-10001774 | CS-10001775 |
| Material | PS | Topas |
| Material chip body | mcs-PS 17 | Mcs-COC 13 |
| Material chip lid | mcs-foil 075 (PS; 125 µm) | mcs-foil 011 (Topas; 140 µm; Tg 78°C) |
| Color | Transparent | Transparent |
| Interface type | Mini Luer interface | Mini Luer interface |
| Surface treatment | Not treated | Not treated |
| Membrane | no membrane | no membrane |
| Design element | Channel | Channel |
Documentation
Zebrafish Chip - Organism-on-a-Chip Fluidic 1371 datasheet
Check the chemical compatibilities for this product here:
Polystyrene - Chemical Compatibility Chart
Topas - Chemical Compatibility Chart
