The LSPone+ HD combines ultra-stable flow performance with larger syringe capacity, making it the ideal choice for long-duration or continuous flow experiments. With 13.5x higher microstepping (43 200 steps/mm), it ensures smooth motion and excellent flow stability, even at ultra-low rates. Designed specifically for use with 2.5 mL and 5 mL syringes, it is the high-precision solution for microfluidic and laboratory workflows requiring extended volume handling.
Includes the LSPone+, power supply, software, your choice of 2.5 or 5 mL glass syringe, USB cable, and syringe change tool. Fittings must be ordered separately.
General
The LSPone+ HD High-Precision Syringe Pump is optimized for delivering ultra-smooth, pulseless flow in microfluidic applications, now with the added advantage of supporting larger syringe volumes. Its enhanced microstepping capability enables precise dosing from the nanoliter range up to 50 mL/min, making it well suited for continuous perfusion, reagent delivery, or long-running biological experiments.
Equipped with an integrated zero-dead-volume rotary valve, the LSPone+ HD enables easy switching between multiple fluids with minimal carryover. Its intuitive interface and compact size allow for seamless integration into laboratory systems, offering high-end performance without the complexity of traditional pump assemblies.
| Syringe volume |
Min. flow rate |
Max. flow rate |
Min. dosing volume |
| 2.5 mL |
0.359 µL/min |
25 mL/min |
5 µL |
| 5 mL |
0.717 µL/min |
50 mL/min |
10 µL |
Features
- Ultra‑stable flow down to sub-microliter levels thanks to HD microstepping
- Optimized for 2.5 mL and 5 mL syringe volumes, ideal for continuous flow
- Zero-dead-volume rotary valve with 6, 8, or 12 ports
- Excellent chemical compatibility: PTFE, PCTFE, borosilicate glass
- Fully programmable via GUI, Python, or LabVIEW
- Plug-and-play setup with USB connectivity and compact footprint
Exceptional Flow Stability
Unlike traditional syringe and peristaltic pumps that often produce pulsatile or unstable flow at ultra-low rates, the LSPone HD achieves unprecedented stability thanks to its enhanced resolution.
With the LSPone HD, there's no need for flow dampers, pressure sensors, or closed-loop control. You get:
✅ Pulseless, stable flow across the entire range
✅ Direct volumetric control without pressure drift
✅ Reliable performance for sensitive applications like organ‑on‑chip, single-cell experiments, and gradient generation
Result: A cleaner baseline, better reproducibility, and greater control over your experimental conditions, especially at the nanoliter scale.
Applications
Sequential injection
The LSPone is ideal for automated sequential injections in multi-step chemical workflows. Its programmable functionality enables precise control over both timing and volume, making it well-suited for executing complex protocols with high reproducibility. Typical applications include surface functionalization, coating processes, and advanced techniques in spatial biology.
Volumetric injection
For applications demanding precise volumetric control, the LSPone ensures highly accurate liquid injections. This capability is especially valuable during sample preparation, where delivering exact reagent volumes is essential for consistency and performance. Common use cases include droplet microfluidics and microparticle synthesis (LNPs, EVs).
Dilution
The programmable control of the LSPone enables the automated preparation of complex mixtures and precise dilutions of samples or reagents. This streamlines workflows, enhances reproducibility, and significantly reduces the need for manual handling. Typical applications include gradient generation, buffer exchange, and sample preparation.
See the Documentation tab for Application Notes and Articles featuring the LSPone.
Special Offer
Get a special discount when purchasing 2 LSPone pumps together!
Content
1× LSPone+ body with rotary valve (PCTFE/PTFE, Ø 0.5 mm)
1× Glass syringe (2.5 mL or 5 mL)
1× Syringe change tool
1× Power supply with regional plug
1× USB cable
LSPoneQuick software (Windows compatible)
Note: Fittings sold separately.
Specifications
| Max Pressure |
7 bars (102 psi) |
| Wetted Materials |
PTFE or UHMW‑PE, PCTFE, borosilicate glass |
| Syringe Size |
2.5 mL – 5 mL |
| Dead Volume |
None (zero‑dead‑volume valve) |
| Plunger Travel & Steps |
30 mm - 1 296 000 micro‑steps |
| Plunger Drive |
Screw drive with linear encoder |
| Accuracy |
< 1 % deviation full stroke |
| Minimum Dosing Volume |
0.1 – 2 µL (depending on syringe) |
| Valve Ports & Channel Size |
6 / 10 / 12 ports; Ø 0.5 / 1.0 mm |
| Tube Fittings |
1/4‑28 UNF flat‑bottom |
| Interface |
USB‑mini, RS232/RS485 over USB |
| Power Consumption |
18–24 VDC, 2.2 A peak, 40 W |
| Stroke Time Range |
6 s – 6 400 min |
| Operating Temp. |
15 – 45 °C (59–113 °F) |
| Operating Humidity |
20 – 80 % non‑condensing |
| Dimensions (L×W×H) |
247×147×85 mm |
| Weight |
2.2 kg |
| Software/OS |
LSPoneQuick; Windows 10+ (also supports Python & LabVIEW) |
| Certifications |
CE & CB |
Note: Valve configurations and syringe sizes are selectable. Specifications may vary slightly depending on configuration and fluid type.
Valve specifications
| Valve configuration |
Zero dead-volume multi-port distribution with angular encoder |
| Number of ports |
6 |
10 |
12 |
| Channel diameter |
0.5 mm |
0.5 mm |
1.0 mm |
0.5 mm |
| Internal volume |
3.6 µL |
4.6 µL |
15 µL |
4.6 µL |
| Carryover volume |
2.6 µL |
2.8 µL |
8 µL |
2.8 µL |
| Tube port fittings |
Standard 1/4-28 UNF, flat-bottom |
| Dead volume |
None |
| Valve body material |
PTFE |
| Valve plug material |
PCTFE |
| Max. pressure |
7 bar (102 psi)
|
Note: Valve configurations and syringe sizes are selectable. Specifications may vary slightly depending on configuration and fluid type.
Documentation
LSPone brochure
LSPone operating manual
LSPone quick start guide
LSPoneQuick software manual
Maintenance guide
STEP file available on request.
