Cross-Flow Membrane Chip - Organ-on-Chip and more Fluidic 653

The Cross-Flow Membrane Chip - Organ-on-Chip and more Fluidic 653 is a versatile microfluidic device designed for advanced biological experiments. Its main purpose is to provide two independent chambers that interact via a permeable membrane, enabling applications such as cell co-culture, filtering, and migration studies. Unique selling points include precise chamber volume management, selectable membrane types, and customizable fluid access through multiple inlets and outlets. Each unit supports dual-channel operation, supporting simultaneous but independent experiments or reagent feeds.

General

The cross-flow membrane chip Fluidic 653 possesses two independent chambers that interact through a permeable membrane. Each chamber features one main inlet and outlet, along with two additional (optional) inlets and outlets for additional reagent supply. The chip is available with different membrane types, varying in characteristics such as pore size. Fluidic 653 can be utilized, for instance, in cell culture experiments, where cells, such as epithelial cells, are co-cultured. The chip is also ideal for applications like filtering, size exclusion, or migration studies. The cross-flow membrane chip Fluidic 653 can be ordered as an open system for self-assembly.

Features & Benefits

• Dual-Chamber Design: Supports two independent yet interacting fluidic chambers for complex biological assays, such as co-culture or migration studies.
• Customizable Membrane Selection: Multiple membrane types are available, allowing users to select based on pore size and material for specific filtration or separation tasks.
• Flexible Fluid Access: Each chamber features one main plus two optional inlets and outlets, giving users control over reagent introduction and collection during experiments.
• Open System Option: Available as an open chip for self-assembly, useful for advanced research setups requiring full customization and integration.
• Chemically Resistant Materials: Constructed from Topas or PS with high-quality COC and PET components, ensuring compatibility with a range of chemicals.
• Mini Luer Interface: Standardized connections simplify integration into existing fluidic systems.
• Surface Treatment Flexibility: Chips are available with hydrophilized or non-treated surfaces, meeting specific biological or chemical assay requirements.

This cross-flow membrane chip offers a solution for complex biological and chemical experiments demanding precise compartmentalization and exchange across a flexible barrier. Researchers can perform co-cultures, migration assays, or filtration tasks within a compact and robust chip. The wide selection of membrane pore sizes and materials enhances compatibility with many applications, from size exclusion to specialized organ-on-chip studies.The chip’s design supports self-assembly, allowing users to further adapt it for their research needs. Its compatibility with standard fluidic connections (Mini Luer) streamlines deployment in laboratory workflows.

Applications

The Cross-Flow Membrane Chip - Organ-on-Chip and more Fluidic 653 is ideal for:

• Organ-on-chip and cell co-culture studies
• Filtration and size exclusion research
• Migration and chemotaxis studies
• Drug testing and compound screening
• Biological barrier modeling
• Membrane permeability assays

Content

1x Cross-Flow Membrane Chip - Organ-on-Chip and more Fluidic 653

Specifications

Documentation

Cross-Flow Membrane Chip - Organ-on-Chip and more Fluidic 653 datasheet

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Check the chemical compatibilities for this product here:
Topas - Chemical Compatibility Chart
Polystyrene - Chemical Compatibility Chart