The Gradient Generator Chip is a microfluidic device designed to generate a concentration gradient within a monitoring chamber. Its unique selling points include a flexible volume setup provided by three inlet ports, precise volume selection through controlled flow rates, and a single outlet for streamlined channel output. With its multi-channel design, users can efficiently administer a range of analyte or drug concentrations across cells of interest.
General
The gradient generator chip Fluidic 1744 with three inlet ports and one outlet port enables the generation of a concentration gradient within the monitoring chamber. For example, it is the perfect tool to investigate the effect of a continuum of concentrations of an analyte or drug on your cells of interest. The lower the flow rate is set within the system, the more diffuse the gradient becomes due to an increased residence time.
Features & Benefits
- Flexible Gradient Formation: Generate a continuous range of analyte or drug concentrations for precise experimentation in one run.
- User-Defined Flow Control: Easily adjust flow rates to manipulate gradient sharpness, supporting a broad spectrum of test conditions.
- Compatible Interface: The mini Luer interface simplifies chip integration with standard laboratory equipment.
- Multiple Material Options: Available in PS and Topas to suit compatibility needs with diverse reagents and workflows.
- Optimized for Cell Studies: Designed for real-time study of cellular responses to varying chemical environments within a controlled microfluidic chamber.
This chip is built for laboratory professionals who need to create and analyze concentration gradients. It provides an efficient, reproducible system for studying cell response to chemicals or drugs in a microfluidic setting. The chip's three inlets allow precise gradients, while the outlet ensures streamlined sample collection.
Its flexible design, offered in both PS and Topas with various surface treatments, supports workflows in pharmacology, cell biology, and bioengineering. Researchers can alter flow rates to adjust gradient resolution, making it suitable for a wide variety of experimental approaches.
Applications
The Gradient Generator Chip is ideal for any laboratory where controlled concentration gradients are required. Its main use cases include:
- Drug dosing studies
- Cell stimulation and response assays
- Toxicology screening
- Biochemical pathway analysis
Content
1x Gradient Generator Chip
Specifications
| SKU | CS-10002198 | CS-10002199 | CS-10002200 | CS-10002197 |
| Design element | Chamber | Chamber | Chamber | Chamber |
| Material | PS | Topas | PS | Topas |
| Material chip body | mcs-PS 17 | mcs-COC 16 | mcs-PS 17 | mcs-COC 16 |
| Material chip lid | mcs-foil 075 (PS; 125 µm) | mcs-foil 011 (Topas; 140 µm; Tg 78°C) | mcs-foil 075 (PS; 125 µm) | mcs-foil 011 (Topas; 140 µm; Tg 78°C) |
| Color | Transparent | Transparent | Transparent | Transparent |
| Interface type | Mini Luer interface | Mini Luer interface | Mini Luer interface | Mini Luer interface |
| Surface treatment | Not treated | Hydrophilized | Hydrophilized | Not treated |
| Membrane | no membrane | no membrane | no membrane | no membrane |
