A pack of 3 focused flow (or flow focusing) droplet generators in glass with sideconnect interface to be used with the Sideconnect chip holder.
Available uncoated (hydrophilic) or with a hydrophobic coating, and nozzle sizes of 10 µm, 50 µm or 75 µm.
General
Focused flow droplet generators are widely used in microfluidics to generate highly monodisperse droplets of various sizes. This Micronit chip offers the following features:
- Manufactured from high-quality borosilicate glass, inert to most chemicals and biocompatible
- Precision-etched microfluidic channels for reproducible results
- Three nozzle sizes: 10 µm (9-20 µm droplet range), 50 µm (40-90 µm droplet range) or 75 µm (65-140 µm droplet range)*
- Sideconnect interface: flow is less disrupted than with perpendicular connection ports, ideal for droplet reinjection
- Optimized nozzle geometry: etched on both sides (oval shape), stable and highly monodisperse droplet generation
- Uncoated (hydrophilic) for oil-in-water (O/W) droplet generation, or coated (hydrophobic) for water-in-oil (W/O) droplet generation
*Indicated reference droplet sizes are based on a reference experiment with Silicone oil 5cSt and DI water combined with 2% v/v Tween 20 or Tween 80.
| Nozzle height |
10 µm |
50 µm |
75 µm |
| Nozzle width |
14 µm |
72 µm |
105 µm |
| Channels height (all channels except nozzle) |
17 µm |
83 µm |
125 µm |
| Inlet/outlet width |
367 µm |
433 µm |
475 µm |
| Junction channels (around the nozzle) width |
22 µm |
88 µm |
130 µm |
| On-chip filter size |
8-10 µm |
no filter |
no filter |
Easily change the droplet size and frequency by tuning the flow rates of the dispersed and continuous phases. These chips are suitable for foam, digital PCR, single-cell analysis, encapsulation, particle and nanoparticle production, etc.
Content
3x Focused flow drop generator - sideconnect
Specifications
|
01365 |
01642 |
01367 |
01640 |
01368 |
01641 |
| Nozzle height |
10 µm
|
50 µm
|
75 µm
|
| Hydrophobic coating |
No |
Yes |
No |
Yes |
No |
Yes |
| Nozzle width |
14 µm |
72 µm |
105 µm |
| Channels height (all channels except nozzle) |
17 µm |
83 µm |
125 µm |
| Inlet/outlet width |
367 µm |
433 µm |
475 µm |
| Junction channels (around the nozzle) width |
22 µm |
88 µm |
130 µm |
| On-chip filter size |
8-10 µm |
no filter |
no filter |
| Chip material |
Borosilicate glass |
| Interface type |
Sideconnect
|
| Chip dimensions |
15x15 mm |
| Chip thickness |
1800 µm |
| Inlets / outlets |
3 / 1
Use a T- or Y-junction to connect the two inlets of the continuous phase
|
| Compatible holder |
Sideconnect chip holder |
Documentation
?FF droplet generator sideconnect 10 µm - technical drawing
?FF droplet generator sideconnect 50 µm - technical drawing
?FF droplet generator sideconnect 75 µm - technical drawing
?Droplet generation - white paper
?How to prevent clogging?
?Using the right surfactants in your droplet generator
?Finding the right flow rates in your droplet generator
?Surface wetting properties
Amoyav, B., & Benny, O. (2018). Controlled and tunable polymer particles’ production using a single microfluidic device. Applied Nanoscience, 8(4), 905-914. https://doi.org/10.1007/s13204-018-0790-0
Lucio, A. A., Mongera, A., Shelton, E., Chen, R., Doyle, A. M., & Campàs, O. (2017). Spatiotemporal variation of endogenous cell-generated stresses within 3D multicellular spheroids. Scientific reports, 7(1), 1-11. https://doi.org/10.1038/s41598-017-12363-x
